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- Bio4PURConti, a pioneering EU-funded project, aims to develop the world’s first continuous production process for bio-based aniline
- Project targets semi-industrial scale production of bio-based aniline, a low-carbon drop-in replacement for conventional aniline
- Covestro coordinates a 10-partner, 7-country consortium with pilot plants in Ghent and Leverkusen
Covestro has launched Bio4PURConti, acting as project coordinator of the pioneering EU-funded initiative. The project aims to develop the world's first continuous production process for bio-based aniline. Aniline is a key raw material for the plastics and chemical industry, notably for MDI, a core building block for polyurethanes.
Fossil-based aniline production generates approximately 20 million tonnes of CO₂ emissions annually worldwide. To specifically reduce the carbon footprint of aniline production, Covestro uses a tailored microorganism in its bio-based process that converts industrial sugars from plant-based biomass into an intermediate product through fermentation. In a second step, chemical catalysis converts this intermediate into aniline with 100% plant-based carbon.
Continuous Fermentation Process: A Technological Breakthrough
Bio4PURConti aims to take this a step further: instead of the fed-batch method used so far, in which raw materials are added and product harvested in stages, the project targets a continuous fermentation technology for the first time. By using plant-based sugars, e.g. from hardwood biomass, it offers a renewable feedstock pathway. The resulting bio-based aniline is fully drop-in compatible with existing polyurethane value chains, meeting MDI specifications without requiring changes to downstream processes, making it a powerful lever for defossilization well beyond the chemical industry itself. The project scales from lab to 1.5 m³ semi-industrial demonstration at Bio Base Europe Pilot Plant and Covestro, integrating cell recycling, real-time analytics and downstream processing. Key objectives include higher space-time yields and significant improvement in product carbon footprint.
"Bio4PURConti is a landmark project not just for Covestro or the aniline market, but for the entire field of industrial biotechnology," says Dr. Markus Dugal, Head of Process Technology at Covestro. "Demonstrating continuous fermentation at semi-industrial scale for a high-volume raw material like aniline will set a new benchmark for what biotech processes can achieve in the chemical industry. Biology and engineering, when combined at scale, can fundamentally reshape how we produce the materials the world depends on."
A Consortium Driving European Biotech Leadership
The 10-partner consortium, spanning 7 countries, brings together leading industrial and academic organisations: Covestro Deutschland AG (Germany), Fibenol Imavere OÜ (Estonia), University of Stuttgart (Germany), Bio Base Europe Pilot Plant VZW (Belgium), Center for Advisory Systems in Technology, Dortmund e.V. – ZEDO (Germany), Norwegian University of Science and Technology – NTNU (Norway), Axel'One (France), VTT Technical Research Centre of Finland Ltd (Finland), Cluster Industrial Biotechnology – CLIB (Germany), and Asociación Española de la Innovación en el Marketing y la Inversión Sostenible – AEIMIS (Spain).
The project has a total budget of €8.4 million, with €7 million in EU funding, and runs for 42 months. Together, the consortium aims to significantly reduce the Product Carbon Footprint (PCF) of aniline in the future. As one of the world's leading aniline producers with a production capacity of over one million tonnes per year, Covestro is uniquely positioned to drive this transformation towards a more sustainable aniline production.
Funded by the European Union. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or the Circular Bio-based Europe Joint Undertaking (CBE JU). Neither the European Union nor the granting authority can be held responsible for them.
This project has received funding from the Circular Bio-based Europe Joint Undertaking under the European Union's Horizon Europe research and innovation programme under Grant Agreement No. 101292477.
The project is supported by the Circular Bio-based Europe Joint Undertaking and its members.
About Covestro:
Covestro is one of the world’s leading manufacturers of high-quality polymer materials and their components. With its innovative products, processes and methods, the company helps enhance sustainability and the quality of life in many areas. Covestro supplies customers around the world in key industries such as mobility, building and living, as well as the electrical and electronics sector. In addition, polymers from Covestro are also used in sectors such as sports and leisure, telecommunications and health, as well as in the chemical industry itself.
The company is geared completely to the circular economy. In addition, Covestro aims to achieve climate neutrality for its Scope 1 and Scope 2 emissions by 2035, and the Group’s Scope 3 emissions are also set to be climate neutral by 2050. Covestro generated sales of EUR 12.9 billion in fiscal year 2025. At the end of 2025, the company had 46 production sites worldwide and employed approximately 17,600 people (calculated as full-time equivalents).
Note: This story has not been edited by The Polymerupdate Editorial team and is auto-generated from a syndicated feed.